I broke my neck last Dec. 27th and am still recovering; I was in quite a bit of pain for many reasons; the HALO kept loosening, and had to be tightened, which entailed an 8 hour round trip to the hospital and back, which was painful, going and returning. Also, I also had to get my gall bladder removed as I developed gall stones. Then when I was well enough to walk, the blown disks in my lower back started giving me a lot of pain. I eventually figured out this was caused by my walker after a few months. I should have known much sooner, but I’m not that smart. In any case, Conolidine relieved my pain far better than opioids and without causing constipation problems. I also like that it’s non-addictive and fast-acting, much faster than pills (that didn’t work anyway ), and a single dose works for several hours. I’m using less now, as I’m healing, and I no longer use a walker, but I still use it when I have a flare-up of pain, for whatever reason, bursitis, arthritis, whatever, it works. I use it. I’d recommend it for any persistent pain or recurring pain. I doubt I’d take it for temporary pain, like hitting your thumb hammering a nail; it’s too expensive to waste.