I got the CONOCB2 to help relieve the severe Chronic pain from my back. I was in an accident and have a false spine from L1-S1 made of Cadaver Bones, spacers, plates down front side and Post down the back side. I had to get off of Opioids I had been taking for 12 years and By taking CONOCB2 I was able to get off Opioids. I still hurt all the time but it is now manageable with no side effects. It took about 4-5 days to be able to walk without hurting. The low back still hurts but is manageable. I would recommend it for anyone on Opioids.