I ordered the clinical strength CONOCB2 in drops and topical. So far I have used 2 bottles of drops and about 1/3 the jar of topical. I have noticed a decrease in pain levels and expect more with time. I also ordered the GABASOM+ sleep support drops. I do seem to sleep soundly when I use them before bed. I fall asleep faster I know. I’ve been using the topical mainly on my arthritic left thumb joint that nothing has helped. It has lowered the discomfort significantly.